Program

Program

THURSDAY – Sep 27th
16:00 – 17:30 PSY1 – Pre-symposium: Sirius and the new opportunities in biophysics
Chair: Chuck Farah
PSY1.1 – Carla Polo (LNLS): From macromolecules to cells: 3D imaging using coherent X-ray diffraction at Cateretê beamline (Sirius)
PSY1.2 – Ana Carolina de Mattos Zeri (LNLS): Macromolecular Crystallography at Sirius – frontiers and challenges for data collection and sample preparation at Manacá beamline
PSY1.3 – Maria Cristina Nonato (USP): X-ray crystallography fragment screening. Opportunities for Manacá beamline (Sirius)
16:30 – 18:00 Registration
18:00 – 19:00 PL01 – Opening lecture: Angela Gronenborn (Univ. Pittsburgh): “Not so crystal clear – crystallins and cataract”
Chair: Antonio José Costa Filho (USP)
19:00 – 21:00 Poster session
FRIDAY Sep 28th
TIME ROOM 1 ROOM 2
8:00 – 9:00 Registration
8:30 – 10:30 SY1 – Cell and model membranes Biophysics
Chair: Karin Riske (UNIFESP)
SY2 – Central Nervous System Electrophysiology
Chair:
SY1.1 – Adriana Fontes (UFPE): Optical Tweezers: Shining Light to Cell Biology SY2.1A – Leonardo Cirqueira Pimentel (UNB): State-dependant affinity for general anesthetics dictates channel sensitivity 
SY2.1B – To Be anounced
SY1.2 – Koji Kinoshita (Univ. South. Denmark): Red Blood Cell Membrane: Mechanical Property Change and Cytoskeletal Network Reformation Under Photosensitizer-mediated Oxidative Stress of Cis-Porphyrin SY2.2 – Melina Pires (USP): Nitrergic Modulation of Magnocellular Neurons from the Supraoptic Nucleus
SY1.3 – Nuno Santos (Univ. Lisbon): Arterial hypertension and stroke patients present Higher erythrocyte adhesion forces, contributing to cardiovascular risk SY2.3 – Christopher Kushmerick (UFMG): Ionotropic actions of Metabotropic Glutamate Receptors
SY1.4 – Luis Bagatolli (Univ. Nac.Córdoba): The cell as a gel: materials for a conceptual discussion SY2.4 – Ricardo Leão (USP): Creating rest and unrest: distinct ways to create stable and unstable membrane potential in neurons
10:30 – 11:00 Coffee Break
11:00 – 13:00 SY3 – Lipid-protein interactions in mimetic systems
Chair: Pietro Ciancaglini (USP)
SY4 – Nanostructures and Drug Delivery
Chair: Daniele Araújo (UFABC)
SY3.1 – Thierry Granjon (Univ. Lyon): Cardiolipin and mitochondrial proteolipidic platforms: toward a mitochondrial raft-like organization? SY4.1 – Renata Lopes (USP): Iontophoresis impact on topical delivery of nanoparticles
SY3.2 – André Luis Ambrosio (USP): Human MPC2 as an autonomous membrane transporter SY4.2 – Marcelo Morales (UFRJ): Nanoparticle-mediated gene delivery for the lung
SY3.3 – Manuel Prieto (Univ. Lisbon): Surface crowding and membrane remodeling by IAPP SY4.3 – Omar Mertins (UNIFESP): Development of functional Nanoparticles for delivery of bioactives
SY3.4 – Mayte Bolean (USP): Biophysical aspects of biomineralization SY4.4 – Ligia Nunes de Morais Ribeiro (UNICAMP): Stability study of Drug Delivery Systems Based on Nanoparticle Tracking Analysis
13:00 – 15:00 Lunch
14:30 – 15:00 Bruker Space
15:00 – 17:00 SY5 – Protein Complexes
Chair: Fábio Almeida (UFRJ)
SY6 – Modern Methods in Computational Biophysics
Chair: Lucas Bleicher (UFMG)
SY5.1 – Ana Paula Valente (UFRJ): Conformational diversity in protein complexes: NMR studies of Allergens Bet v 1 and Fag s 1 with ligands and DIII of Dengue virus E protein with antibodies SY6.1 – Kaline Coutinho (USP): Theoretical Studies of Electronic Structure of Molecules Interacting with Phospholipid Bilayers
SY5.2 – Elio Anthony Cino (UFMG): Role of Hydrogen Bonds in P53 Core Domain Stability and Aggregation SY6.2 – Gerald Weber (UFMG): Mesoscopic models as a Tool for Probing molecular interactions in DNA and RNA
SY5.3 – Rachel Nechushtai (Hebrew Univ.): The role played by the labile 2Fe-2S clusters of neet proteins in controling their structure, function and folding SY6.3 – Rafaela Ferreira (UFMG): Rational Drug Design Towards New Treatments
For Neglected And Emerging Diseases
SY5.4 – Carla Mattos (Northeastern Univ.): Ras dimerization and allosteric modulation of GTP hydrolysis linked in the presence of Raf-RBD and the membrane SY6.4 – Roberto Chica (Univ. Ottawa): Rational Design of Proteins that Exchange on Functional Timescales
17:00 – 17:30 Coffee Break
17:30 – 18:30 PL02 -Plenary – Benoit Roux (Univ. Chicago): Molecular Dynamics Studies of P-type ATPase Ion Pumps
Chair: Carla Mattos
18:30 – 19:30 SBBf General Assembly
     
SATURDAY Sep 29th
TIME ROOM 1 ROOM 2
8:00 – 9:00 Registration
8:30 – 10:30 SY7 – Antimicrobial peptides
Chair: Lucia Bianconi (UFRJ)
SY8 – Photobiology and its application in Health Sciences
Chair:
SY7.1A – Catarina Cataldi: Zika NS2B epitope as a candidate for diffential diagnosis – from Poster SY8.1 – Renato Araújo (UFPE): Optical therapy and medical diagnosis assisted by metallic nanoparticles
SY7.1B – Yeny Yaneth Pillco Valencia: Computational simulation of popg aggregates in the presence of antimicrobial peptide LL-37 – from Poster
SY7.2 – João Ruggiero (UNESP): Lipid-packing perturbation induced by pH-responsive peptide in lipid membranes: effect of pH and peptide chemical modification. SY8.2 -Adenilson de Souza da Fonseca (UFRJ): Low power lasers and LEDs on DNA repair and genomic stability 
SY7.3 – Katia Perez (UNIFESP): Using biomimetical membranes to study the mode of action of peptides SY8.3 – Joao Paulo Tardivo (Faculdade de Medicina do ABC): Is Photodynamic Therapy Efficient to Treat Osteomyelitis in Diabetic Foot?
SY7.4 – Maria Elena Lima (UFMG): A synthetic peptide derived from a toxin of the spider Phoneutria nigriventer: a promising candidate to a therapeutic drug to treat erectile dysfunction SY8.4 – Beate Roder (Univ. Humbolt): Photodynamic inactivation (PDI) of biofilm forming microorganisms
10:30 – 11:00 Coffee Break
11:00 – 13:00 SY9 – Structural and Unstructural Biology
Chair: Rosangela Itri
SY10 – Biophysics of the heart
Chair: Emiliano Madei (UFRJ)
SY9.1 – Garegin Papoian (Univ. Maryland): Assembly and Dynamics of Histone Oligomers and Nucleosomes SY10.1 – Danilo Campos (UNIFESP): Keep your heart stressed: impaired superoxide production and pathogenesis of Chagas disease
SY9.2 – Vladimir Uversky (Univ. South Florida): Unusual Biophysics and Strange Biology of Intrinsic Disorder SY10.2 – Rosana Bassani (UNICAMP): Proarrhyhmic effects of Doxorubicin in the myocardium
SY9.3 – Yraima Cordeiro (UFRJ): Prion protein and alpha-synuclein aggregation in vitro: characterization of therapeutic compounds and cofactors for protein misfolding SY10.3 – Micaela Lopez Alarcón (UFABC): The role of NLRP3/Casp1/IL-1β axis in renal ischemia/reperfusion-induced cardiac electrical disturbances
SY9.4 – Glaucia Pinheiro (UNICAMP): NMR structure of the J-domain of co-chaperone Sis1 from Saccharomyces cerevisiae SY10.4 – Emiliano Medei (UFRJ): Cardiac electrical and mechanical study on a type 2 diabetes experimental model
13:00 – 15:00 Lunch
14:30 – 15:00 NANOTEMPER: Binding Characterization trough MicroScale Thermophoresis… in any buffer!
15:00 – 17:00 SY11 – Methods in Biophysics
Chair: Paulo Bish (UFRJ)
SY12 – Nanostructures
Chair: Luciana M. Rebelo Alencar (UFMA)
SY11.1 – Paul Whitford (Northeastern Univ.): Quantifying collective dynamics in the ribosome SY12.1 – Alan Dalton (Univ. Sussex): Biological functionalization of synthetic nanoparticles using novel 2D peptide assemblies
SY11.2 – Marin van Heel (Imp. College): Dynamic Structures of Biological Nano-Machines by Single-Particle Cryo-EM SY12.2 – Leandro RS Barbosa (USP): Cubosomes as delivery for many drugs
SY11.3 – Fabio Gozzo (UNICAMP): Advances in Mass Spectrometry as a Structural Biology Tool SY12.3 – Frederic Frezard (UFMG): Targeting the host-cell for improved therapy of leishmaniasis
SY11.4 – Roberto Salinas (USP): Solution NMR spectroscopy studies of the Na+/Ca2+exchanger SY12.4 – Daniele Araújo (UFABC): Thermosensitive hydrogels and organogels: from supramolecular structure to new drug-delivery systems
17:00 – 17:30 Coffee Break
17:30 – 18:30 PL03 – Plenary – Anibal Vercesi (UNICAMP): The redox nature of the mitochondrial permeability transition
Chair: Mauricio da S. Baptista (USP)
18:30 – 20:30 Poster Session
     
SUNDAY Sep 30th
TIME ROOM 1 ROOM 2
8:30 – 10:30 SY13 – Molecular Modeling and Dynamics
Chair: Ernesto Caffarena (FioCruz)
SY14 – Photodynamic Therapy
Chair: Martha Ribeiro (IPEN)
SY13.1 – Guilherme Arantes (USP): Unfolding metalloproteins with force: From simple models to quantum mechanical calculations  SY14.1 – Juliana Ferreira (UNIVAP): Photodynamic therapy in cutaneous Leishmaniasis
SY13.2 – Werner Treptow (UnB): Binding of Small Ligands to Two State Membrane Proteins SY14.2 – Fabio Parra Sellera (USP): Antimicrobial photodynamic therapy in Veterinary Medicine
SY13.3 – Monica Pickholz (Univ. B. Aires): Contributions of Simulations to the Understanding of Drug Delivery Systems SY14.3 – Renata Belotto (Hospital Perola Byington): Can the photodynamic therapy be an alternative to treat high grade cervical intraepithelial neoplasia?
SY13.4 – Sergio Pantano (Pasteur): Towards a Complete Coarse-Grained Force Field for Biosimulations SY14.4 – Silvia Nunez (Un. Brasil): Antimicrobial Photodynamic Therapy
10:30 – 11:00 Coffee Break
11:00 – 12:00 PL04 – Plenary – Joke Bouwstra (Leiden): Lipid organization in the skin barrier in health and disease
Chair: Eneida de Paula (UNICAMP)
12:00 – 14:00 Lunch
14:00 – 16:00 SY15 – Biophysics of Proteins
Chair: Nuno Santos (IMM)
SY16 – Cellular Biophysics
Chair: Gilberto Weismuller (UFRJ)
SY15.1 – Carlos Ramos (UNICAMP): Chaperone-assisted protein aggregate reactivation SY16.1 – Celso Caruso (UFRJ): albumin handling in renal proximal tubule cells: central role in the progression of renal disease
SY15.2 – Chuck Farah (USP): Structural and Functional Studies on the Xanthomonadaceae Type IV Secretion System – a Bacteria Killing Machine SY16.2 – Fernando Abdulkader (USP): Ion channels in the amplifying pathway of insulin secretion
SY15.3 – Jorge Pereira (UNESP): Are Ionic Liquids Good Protein Stabilizers? SY16.3 – Felipe Leite (USP): post-translational arginylation and inter-sarcomere dynamics in skeletal muscle myofibrils
SY15.4 – Rosana Chehin (CONICET-UNT): Biophysical characterization of doxycycline potential neuroprotective mechanism SY16.4 – Adriano Mesquita (USP): Dynamics of cardiomyocytes obtained by the method of traction force microscopy
16:00 – 16:30 Closing and awards ceremony