Program

Program

THURSDAY – Sep 27th
16:00 – 17:30 Pré-symposium: Sirius and the new opportunities in biophysics
Ana Carolina de Mattos Zeri (LNLS): Macromolecular Crystallography at Sirius – frontiers and challenges for data collection and sample preparation at Manacá beamline
Maria Cristina Nonato (USP): X-ray crystallography fragment screening. Opportunities for Manacá beamline (Sirius)
Carla Polo (LNLS): From macromolecules to cells: 3D imaging using coherent X-ray diffraction at Cateretê beamline (Sirius)
16:30 – 18:00 Registration
18:00 – 19:00 Opening lecture: Angela Gronenborn (Univ. Pittsburgh): “HUMAN ΒB2-CRYSTALLIN FORMS A FACE-EN-FACE DIMER IN SOLUTION: AN INTEGRATED NMR AND SAXS STUDY”
     
FRIDAY Sep 28th
TIME ROOM 1 ROOM 2
8:00 – 9:00 Registration
9:00 – 11:00 Cell and model membranes Biophysics Central Nervous System Electrophysiology
Adriano Mesquita (USP): DYNAMICS OF CARDIOMYOCYTES OBTAINED BY THE METHOD OF TRACTION FORCE MICROSCOPY Ricardo Leão (USP): Creating rest and unrest: distinct ways to create stable and unstable membrane potential in neurons
Adriana Fontes (UFPE): Optical Tweezers: Shining Light to Cell Biology Melina Pires (USP): Nitrergic Modulation of Magnocellular Neurons from the Supraoptic Nucleus
Koji Kinoshita (Univ. South. Denmark): Red Blood Cell Membrane: Mechanical Property Change and Cytoskeletal Network Reformation Under Photosensitizer-mediated Oxidative Stress of Cis-Porphyrin Christopher Kushmerick (UFMG): Ionotropic actions of Metabotropic Glutamate Receptors
Nuno Santos (Univ. Lisbon): ARTERIAL HYPERTENSION AND STROKE PATIENTS PRESENT HIGHER ERYTHROCYTE ADHESION FORCES, CONTRIBUTING TO CARDIOVASCULAR RISK 2 from the abstracts
11:00 – 11:30 Coffee Break
11:30 – 13:30 Biophysics of Proteins Nanostructures and Drug Delivery
Carlos Ramos (UNICAMP): CHAPERONE-ASSISTED PROTEIN AGGREGATE REACTIVATION Renata Lopes (USP): Iontophoresis impact on topical delivery of nanoparticles
Carla Mattos (Northeastern Univ.): Ras dimerization and allosteric modulation of GTP hydrolysis linked in the presence of Raf-RBD and the membrane Daniele Araújo (UFABC): Thermosensitive hydrogels and organogels: from supramolecular structure to new drug-delivery systems
Ana Paula Valente (UFRJ): Conformational diversity in protein complexes:  NMR studies of Allergens Bet v 1 and Fag s 1 with ligands and DIII of Dengue virus E protein with antibodies Omar Mertins (UNIFESP): DEVELOPMENT OF FUNCTIONAL NANOPARTICLES FOR DELIVERY OF BIOACTIVES
Glaucia Pinheiro (UNICAMP): NMR structure of the J-domain of co-chaperone Sis1 from Saccharomyces cerevisiae Ligia Ribeiro (UNICAMP): to be announced
13:30 – 15:00 Lunch
15:00 – 17:00 Protein Complexes Modern Methods in Computational Biophysics
Jorge Pereira (UNESP): Are Ionic Liquids Good Protein Stabilizers? Kaline Coutinho (USP): to be announced
Rachel Nechushtai (Hebrew Univ.): THE ROLE PLAYED BY THE LABILE 2Fe-2S CLUSTERS OF NEET PROTEINS IN CONTROLING THEIR STRUCTURE, FUNCTION AND FOLDING

Gerald Weber (UFMG): MESOSCOPIC MODELS AS A TOOL FOR PROBING MOLECULAR INTERACTIONS IN DNA AND RNA

Elio Anthony Cino (UFMG): Role of Hydrogen Bonds in P53 Core Domain Stability and Aggregation

Rafaela Ferreira (UFMG): RATIONAL DRUG DESIGN TOWARDS NEW TREATMENTS

FOR NEGLECTED AND EMERGING DISEASES

Chuck Farah (USP): STRUCTURAL AND FUNCTIONAL STUDIES ON THE XANTHOMONADACEAE TYPE IV SECRETION SYSTEM – A BACTERIA KILLING MACHINE Roberto Chica (Univ. Ottawa): Rational Design of Proteins that Exchange on Functional Timescales
17:00 – 17:30 Coffee Break
17:30 – 18:30 Plenary – Benoit Roux (Univ. Chicago): Molecular Dynamics Studies of P-type ATPase Ion Pumps
18:30 – 20:30 Poster Session
     
SATURDAY Sep 29th
TIME ROOM 1 ROOM 2
8:00 – 9:00 Registration
9:00 – 11:00 Antimicrobial peptides Photobiology and its application in Health Sciences
Maria Elena Lima (UFMG): A synthetic peptide derived from a toxin of the spider Phoneutria nigriventer: a promising candidate to a therapeutic drug to treat erectile dysfunction Beate Roder (Univ. Humbolt): Photodynamic inactivation (PDI) of biofilm forming microorganisms
João Ruggiero (UNESP): Lipid-packing perturbation induced by pH-responsive peptide in lipid membranes: effect of pH and peptide chemical modification. Fabio Parra Sellera (USP): Antimicrobial photodynamic therapy in Veterinary Medicine
Katia Perez (UNIFESP): Using biomimetical membranes to study the mode of action of peptides Juliana Ferreira (UNIVAP): Photodynamic therapy in cutaneous Leishmaniasis
Ederlan Ferreira (UFBA): In vitro and in silico studies of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitory activity of the beans peptides Renato Araújo (UFPE): Optical therapy and medical diagnosis assisted by metallic nanoparticles
11:00 – 11:30 Coffee Break
11:30 – 13:30 Amyloid fibril, unstructured proteins Biophysics of the heart
Vladimir Uversky (Univ. South Florida): Unusual Biophysics and Strange Biology of Intrinsic Disorder Danilo Campos (UFRJ): Keep your heart stressed: impaired superoxide production and pathogenesis of Chagas disease
Garyk Papoian (Univ. Maryland): Assembly and Dynamics of Histone Oligomers and Nucleosomes Rosana Bassani (UNICAMP): PROARRHYHMIC EFFECTS OF DOXORUBICIN IN THE MYOCARDIUM
Yraima Cordeiro (UFRJ): Prion protein and alpha-synuclein aggregation in vitro: high-throughput method as tool to select and study therapeutic compounds against neurodegenerative disease Micael Lopez Alarcón (UFRJ): The role of NLRP3/Casp1/IL-1β axis in renal ischemia/reperfusion-induced cardiac electrical disturbances
Rosana Chehin (CONICET-UNT): Biophysical characterization of doxycycline potential neuroprotective mechanism 2 from the abstracts
13:30 – 15:00 Lunch
15:00 – 17:00 Methods in Biophysics Cellular Biophysics
Paul Whitford (Northeastern Univ.): Quantifying collective dynamics in the ribosome Celso Caruso (UFRJ): ALBUMIN HANDLING IN RENAL PROXIMAL TUBULE CELLS: CENTRAL ROLE IN THE PROGRESSION OF RENAL DISEASE
Marin van Heel (Imp. College): Dynamic Structures of Biological Nano-Machines by Single-Particle Cryo-EM

Fernando Abdulkader (USP): ION CHANNELS IN THE AMPLIFYING PATHWAY OF INSULIN SECRETION

Fabio Gozzo (UNICAMP): Advances in Mass Spectrometry as a Structural Biology Tool

Felipe Leite (USP): POST-TRANSLATIONAL ARGINYLATION AND INTER-SARCOMERE DYNAMICS IN SKELETAL MUSCLE MYOFIBRILS

Roberto Salinas (USP): Solution NMR spectroscopy studies of the Na+/Ca2+ exchanger Luis Bagatolli (Univ. Nac.Córdoba): The cell as a gel: materials for a conceptual discussion
17:00 – 17:30 Coffee Break
17:30 – 18:30 Plenary – Anibal Vercesi (UNICAMP): THE REDOX NATURE OF THE MITOCHONDRIAL PERMEABILITY TRANSITION
18:30 – 20:30 Poster Session
20:00 – 21:00 SBBf General Assembly
     
SUNDAY Sep 30th
TIME ROOM 1 ROOM 2
9:00 – 11:00 Molecular Modeling and Dynamics Photobiology and its Applications in Health Sciences
Guilherme Arantes (USP): Unfolding metalloproteins with force: From simple models to quantum mechanical calculations

Silvia Nunez (Un. Brasil): Antimicrobial Photodynamic Therapy

Werner Treptow (UnB): Binding of Small Ligands to Two State Membrane Proteins

Joao Paulo Tardivo (UFABC) : to be announced

Monica Pickholz (Univ. B. Aires): Contributions of Simulations to the Understanding of Drug Delivery Systems Renata Belotto (Hospital Perola Byington): CAN THE PHOTODYNAMIC THERAPY BE AN ALTERNATIVE TO TREAT HIGH GRADE CERVICAL INTRAEPITHELIAL NEOPLASIA?
Sergio Pantano (Pasteur): Towards a Complete Coarse-Grained Force Field for Biosimulations 2 from the abstracts
11:00 – 11:30 Coffee Break
11:30 – 13:30 Lipid-protein interactions in mimetic systems Nanostructures

Thierry Granjon (Univ. Lyon): CARDIOLIPIN AND MITOCHONDRIAL PROTEOLIPIDIC PLATFORMS: TOWARD A MITOCHONDRIAL RAFT-LIKE ORGANIZATION?

Alan Dalton (Univ. Sussex): Biological Functionalisation of Synthetic Nanoparticles Using Novel 2D Peptide Assemblies
André Luis Ambrosio (USP): HUMAN MPC2 AS AN AUTONOMOUS MEMBRANE TRANSPORTER Leandro RS Barbosa (USP): Cubosomes as delivery for many drugs
Manuel Prieto (Univ. Lisbon): Surface crowding and membrane remodeling by IAPP Frederic Frezard (UFMG): TARGETING THE HOST-CELL FOR IMPROVED THERAPY OF LEISHMANIASIS
Mayte Bolean (USP): BIOPHYSICAL ASPECTS OF BIOMINERALIZATION 2 from the abstracts
13:30 – 15:00 Lunch
15:00 – 16:00 Closing Plenary – Joke Bouwstra (Leiden): Lipid organization in the skin barrier in health and disease
16:00 – 16:30 Closing and awards ceremony